石英晶體微天平
產品型號：eQCM-I MiniTM具耗散與阻抗量測功能的石英晶體微天平 (QCM-D)
eQCM-I Mini™ 石英晶體微天平可量測石英晶體共振器及其吸附薄膜的共振頻率與耗散變化。QCM 為高靈敏度質量感測器，可廣泛應用於各種研究，包括生物感測器、化學感測器、腐蝕研究、高分子薄膜、奈米粒子薄膜、蛋白質薄膜、生物膜等。將 QCM與恆電位儀結合使用，可在薄膜內驅動電化學反應，進而產生質量變化。透過將質量變化與化學變化結合分析，可更全面地了解薄膜的各項特性。
eQCM-I Mini 詳細資訊
系統可量測共振頻率及共振導納曲線頻寬。其中，頻寬，亦即半高全寬 (Full Width at Half Maximum, FWHM)，與品質因數 (Q) 具有直接對應關係，而品質因數 (Q) 依定義為耗散 (D) 的倒數。
eQCM-I Mini特色
l 同時量測共振頻率及共振品質（半高全寬、頻寬、耗散）
l 可快速且依序量測不同泛音，5 MHz 石英晶體最高可量測至第 13 泛音。
l 內建溫度控制功能，控制範圍 15°C ~ 60°C ±0.02°C。
l 可選配電化學量測模組，搭配 ITO-QCM 感測器使用。
l 模組化感測器夾具，最多可支援 4 個量測通道。
l 透過 USB 與安裝 Windows® 10/11 的外部電腦連接及控制。
隨附軟體可完整控制eQCM-I Mini系統，並提供兩種量測模式：
1.Resonance（共振模式）︰量測共振曲線，並計算共振頻率及半高全寬，最高量測頻率可達 80 MHz。
2.QCM-t（連續量測模式）︰持續量測共振參數及流通池溫度。
計算功能︰系統可利用標準模型或自訂模型計算多種 QCM 及吸附層相關參數。所有計算結果皆可即時顯示於螢幕、列印、儲存及匯出供後續分析。
標準配備
l eQCM 主機（兩通道，其中一個為溫控通道）
l Microsoft® Surface Pro Tablet (Windows® 10 Pro)
l QSH-014 流通式 QCM 感測器夾具
l QSHE-014 流通式 QCM 感測器夾具配備「無洩漏」銀/氯化銀參考電極
l BioSense EC 3.xx 軟體（單一使用者授權）
* 不包含恆電位儀
技術資訊
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量測原理 |
eQCM-I Mini為高靈敏度質量感測器，可量測石英晶體共振器頻率的變化。作為一種無標記生物感測器，QCM-I 可量測發生於感測器表面或近表面的吸附層濕質量。本系統採用石英晶體阻抗分析原理，可量測共振頻率 (fres)及共振導納曲線頻寬。其中頻寬，或半高全寬 (FWHM) 與品質因數 (Q) 具有直接關係。品質因數(Q)依定義即為耗散 (D) 的倒數。 |
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量測通道數量 |
2 第 1 通道：具溫度控制功能 第 2 通道：可連接多種外部感測器夾具模組 |
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頻率範圍 |
1 ~ 80 MHz，5 MHz 石英晶體最高支援至第 13 泛音。 |
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液體中共振頻率靈敏度 |
≤ 2 x 10-1 Hz |
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液體中耗散靈敏度 |
≤ 1 x 10-7 |
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液體中質量靈敏度 * |
≤ 1 ng/cm2 |
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每個泛音所記錄的參數 |
共振曲線、共振頻率、頻率變化 (ΔFrequency)、半高全寬、半高全寬變化 (ΔFWHM)、品質因數 (Q)、耗散、耗散變化 (ΔDissipation)、溫度等 |
溫度控制
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工作溫度 |
15°C ~ 60°C |
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溫度穩定度 |
± 0.02°C |
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溫度控制 |
手動設定或軟體控制 |
流體與樣品
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流通池容量 |
~ 40 µl（搭配 Ø14 mm 石英晶體時之典型值） |
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接液材質 |
PTFE, PEEK, SS, VITON（或 Kalrez） |
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樣品導入 |
使用者自行配置或整合式選配方案 |
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泵浦 |
使用者自備、注射泵浦或整合式蠕動泵浦選配方案 |
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其他樣品槽選項 |
電化學流通池、開放式培養槽、浸沒式、真空型、高壓型、遠端低外型、橢圓偏光儀、顯微鏡整合、或客製化配置 |
外觀尺寸（不含電腦）
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尺寸、重量 |
180 mm × 175 mm × 68mm, 1.35 kg |
軟體
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BioSense |
適用於QCM及EC量測的通用軟體平台 |
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量測資料匯入 / 匯出 |
可匯出至第三方軟體，包括Excel, JPG, BPM, WMF等 |
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電腦控制 |
USB 2.0, Windows® 10 |
電源
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電源供應 |
12V直流電源供應器，支援全球通用電壓AC 100 ~ 240 V, 50 ~ 60 Hz |
*假設 Sauerbrey 關係式成立的情況下。
所有規格如有變更，恕不另行通知。
Quartz Crystal Microbalance with Impedance Measurement and Dissipation (QCM-D)
The eQCM-I MiniTM Quartz Crystal Microbalance measures the changes in frequency and dissipation of a quartz crystal resonator and any adsorbed film. eQCMs are high-sensitivity mass sensors, useful in any number of applications - biosensors, chemical sensors, corrosion, polymer films, nanoparticle films, protein films, biofilms, etc. Coupling a QCM with a potentiostat allows you to drive electrochemical reactions within the film, thereby producing mass changes. Combining mass changes with chemical changes allows you to more fully characterize your films.
eQCM-I Mini Product Details
The resonant frequency and the bandwidth of the resonant conductance curve are determined. The bandwidth or full width at half maximum, (FWHM) is direct correlation with the quality factor (Q) which is by definition the inverse of the well known dissipation (D).
eQCM-I Mini Features:
l Both the frequency and the quality of resonance (FWHM or bandwidth or dissipation) are measured
l Different harmonics (up to the 13th overtone at 5MHz crystals) can be quickly and sequentially measured
l Temperature control from 15°C to 60°C (± 0.02°C) is included
l EC measurement module is optionally available with ITO-QCM sensors
l Modular sensor holder up to 4 measuring channels
l External PC with Windows® 10/11; communication with QCM-I via USB
The software performs full control of the eQCM-I Mini Instrument. Two measurement modes are available:
1.Resonance: Measurement of resonance curve and calculation of the resonance frequency & FWHM up to 80 MHz
2.QCM-t: Continuous measurement of the resonance parameters and the temperature of the flow-cell.
Calculation: Various eQCM and ad-layer parameters can be calculated using standard or custom made models. All these parameters can be displayed on the screen, printed, saved or can be exported for further evaluation.
What's Included:
l eQCM unit with two channels (one channel is temperature controlled)
l Microsoft® Surface Pro Tablet with Windows® 10 Pro
l QSH-014 QCM Sensor Holder (flow through type)
l QSHE-014 QCM Sensor Holder (flow through type) with "leak free" Ag/AgCl reference electrode
l BioSense EC 3.xx Software (one user license)
*Potentiostat Not Included
TECHNICAL INFORMATION
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Measuring Principle |
The eQCM-I Mini unit is a high sensitivity mass sensor which measures the change in frequency of a quartz crystal resonator and as a label free biosensor it measures the “wet mass” of the adsorbed layer in processes occurring at or near the sensor surface. The measuring principle is based on impedance analysis of the quartz crystal. The resonant frequency (fres) and the bandwidth of the resonant conductance curve are determined. The bandwidth or full width at half maximum (FWHM) is in direct correlation with the quality factor (Q) which is by definition the inverse of the well known dissipation (D). |
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Measurement Channels |
2 1st : Temperature controlled 2nd : Connection for a variety of external sensor-holder modules |
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Frequency Range |
1 ~ 80 MHz, up to the 13th overtone for a 5 MHz Crystal |
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Resonance Frequency Sensitivity in Liquid |
≤ 2 x 10-1 Hz |
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Dissipation Sensitivity in Liquid |
≤ 1 x 10-7 |
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Mass Sensitivity in Liquid * |
≤ 1 ng/cm2 |
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Parameters Recorded for each Overtone |
Resonance Curve, Frequency, ΔFrequency, FWHM, ΔFWHM, Q, Dissipation, ΔDissipation, Temperature, etc. |
Temperature Control
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Working Temperature |
15°C to 60°C |
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Temperature Stability |
± 0.02°C |
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Temperature control |
Set manually or via software |
Fluidic and Sample
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Flow Cell Volume |
~ 40 µl (typical with Ø14 mm crystals) |
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Wetted parts |
PTFE, PEEK, SS, VITON (or Kalrez) |
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Sample Loading |
Customer Supplied or Integrated Options |
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Pump |
Customer Supplied, Syringe Pump or Integrated Peristaltic Options |
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Other Sample Cell Options |
Electrochemical flow-cell, Open Cuvette, Immersion, Vacuum, High-pressure, Remote Low-profile, Ellipsometry, Microscopy, Custom... |
Physical Dimensions (without the computer)
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Dimensions, weight |
180 mm × 175 mm × 68mm, 1.35 kg |
SOFTWARE
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BioSense |
Universal software platform for QCM & EC measurements |
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Import/Export of the measured data |
Export to third party software Excel, JPG, BPM, WMF etc. |
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PC Control |
USB 2.0, Windows® 10 |
ELECTRICAL
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Supply Voltage |
12VDC power supply with universal input voltage (100V to 240V AC & 50 to 60 Hz) |
* The Sauerbrey relation is assumed to be valid.
All specifications are subject to change without notice.
